The NFKB Inducing Kinase Modulates Hematopoiesis During Stress
نویسندگان
چکیده
منابع مشابه
The NFKB Inducing Kinase Modulates Hematopoiesis During Stress.
The genetic programs that maintain hematopoiesis during steady state in physiologic conditions are different from those activated during stress. Here, we show that hematopoietic stem cells (HSCs) with deficiencies in components of the alternative NFκB pathway (the NFκB inducing kinase, NIK, and the downstream molecule NFκB2) had a defect in response to stressors such as supraphysiological doses...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2015
ISSN: 1066-5099
DOI: 10.1002/stem.2066